Package: OpEnHiMR
Type: Package
Title: Optimization Based Ensemble Model for Prediction of Histone
        Modifications in Rice
Version: 0.1.1
Authors@R: c(person("Dipro", "Sinha", role = c("aut","cre"), email = "diprosinha@gmail.com"),
             person("Sneha", "Murmu", role = c("aut")),
             person("Girish Kumar", "Jha", role = c("aut")),
             person("Md", "Yeasin", role = c("aut")),
             person("Saikath", "Das", role = c("aut")),
             person("Sougata", "Bhattacharjee", role = c("aut")),
             person("Dwijesh Chandra", "Mishra", role = c("aut")),
             person("Neeraj", "Budhlakoti", role = c("aut")),
             person("Sudhir", "Srivastava", role = c("aut")),
             person("Sunil", "Archak", role = c("aut")))
Description: The comprehensive knowledge of epigenetic modifications in
        plants, encompassing histone modifications in regulating gene
        expression, is not completely ingrained. It is noteworthy that
        histone deacetylation and histone H3 lysine 27 trimethylation
        (H3K27me3) play a role in repressing transcription in
        eukaryotes. In contrast, histone acetylation (H3K9ac) and
        H3K4me3 have been inevitably linked to the stimulation of gene
        expression, which significantly influences plant development
        and plays a role in plant responses to biotic and abiotic
        stresses. To our knowledge this the first multiclass classifier
        for predicting histone modification in plants.
        <doi:10.1186/s12864-019-5489-4>.
License: GPL-3
Encoding: UTF-8
Imports: Biostrings, devtools, tidyverse, seqinr, splitstackshape,
        entropy, party, e1071, caret, randomForest, gbm, stats,
        stringr, ftrCOOL, dplyr, RCurl
Suggests: testthat (>= 3.0.0)
Config/testthat/edition: 3
NeedsCompilation: no
Packaged: 2026-10-11 09:49:51 UTC; root
Author: Dipro Sinha [aut, cre], Sneha Murmu [aut], Girish Kumar Jha
        [aut], Md Yeasin [aut], Saikath Das [aut], Sougata
        Bhattacharjee [aut], Dwijesh Chandra Mishra [aut], Neeraj
        Budhlakoti [aut], Sudhir Srivastava [aut], Sunil Archak [aut]
Maintainer: Dipro Sinha <diprosinha@gmail.com>
Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev
        libfribidi-dev git make libharfbuzz-dev libgit2-dev libicu-dev
        libjpeg-dev libpng-dev libtiff-dev libuv1-dev libwebp-dev
        libxml2-dev libssl-dev libx11-dev zlib1g-dev
Repository: https://diprosinha.r-universe.dev
Date/Publication: 2024-05-31 02:40:36 UTC
RemoteUrl: https://github.com/cran/OpEnHiMR
RemoteRef: HEAD
RemoteSha: 4f31dd1ee278023079cc1f297c9e9e6cde93f065